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Elke Grassman

Elke Grassman's picture

Main Profile

Full Name and Degrees: 
Elke Grassman, Ph.D., HCLD
Member Role: 
Co-PI/Co-Investigator
Institutional affiliation: 
CCHMC
Hub Site: 
None
Objective: 

Elke Grassman, Ph.D., HCLD
Cincinnati Children's Hospital Medical Center
Assistant Professor, Experimental Hematology and Cancer Biology
Director, Translational Trial Development & Support Laboratory (TTDSL)
3333 Burnet Ave.
ML 7013
Cincinnati, Ohio 45229

Office # (513)636-0958
Fax # (513)636-1446
Elke.Grassman@cchmc.org

research focus: 

Director of Translational Trials Development and Support Laboratory (TTDSL) CAP/CLIA certified. Specialized on development of standardized high complexity testing procedures and provides quality testing of vector and cell products, assay development and safety studies.

Recent publications: 
1.) Pilat S, Carotta S, Schiedlmeier B, Kamino K, Mairhofer A, Will E, Modlich U, Steinlein P, Ostertag W, Baum C, Beug H, Klump H. (2005). HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. PNAS. 102(34):12101-6. PMCID:PMC1189347 2.) Schiedlmeier, B., Klump, H., Will, E., Li, Z., Wang, Z., Rimek, A., Friel, J., Arman-Kalcek, G., Baum, C. and Ostertag, W. (2003) High level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage to human cord blood CD34+ cells, but impairs lymphomyeloid differentiation. Blood, 101(5):1759-68 3.) Will, E., Bailey, J, Schuesler, T., Modlich, U., Balcik, B., Burzynski, B., Witte, D., Layh-Schmitt, G., Rudolph, C., Schlegelberger, B., Von Kalle, C., Baum, C., Sorrentino, B.P., Wagner, L.M., Kelly, P., Reeves, L., and Williams, D.A. (2007). Importance of murine study design for testing toxicity of retroviral vectors in support of Phase I trials. Mol. Ther. ,Apr 15(4):782-91 4.) Galla, M., Will, E., Kraunus, J., Chen, L., and Baum, C (2004). Retroviral pseudotransduction for targeted cell manipulation. Mol Cell, 16: 309-315. (These authors contributed equally to this work)
Profile Page Photo: 
Elke Grassman, Ph.D., HCLD

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