dgarry

Main Profile

Full Name and Degrees:

Daniel J. Garry, M.D., Ph.D.

Member Role:

Lead Principal Investigator

More Info:

Daniel Garry: University of Minnesota

Institutional affiliation:

University of Minnesota

Biography:

Dr. Daniel Garry joins the Consortium from the University of Minnesota where he is the Director of the Lillehei Heart Institute and Chief of the Cardiovascular Division. He is Professor of Medicine and is a member of the Stem Cell Institute and The Developmental Biology Center at the University of Minnesota.

He received his M.D. and PhD from the University of Minnesota and pursued postdoctoral training at UT Southwestern Medical Center at Dallas. Dr. Garry is the holder of the St. Jude Medical Endowed Chair in Cardiovascular Diseases.

Additional links:

http://www.ahc.umn.edu/meet/experts/garry/index.htm|Academic Health Center Expert Guide

Research hub:

Programming and Reprogramming: CV and HSC Fate

Hub Site:

16-Daniel Garry

Objective:

Dr. Daniel Garry (University of Minnesota) and Dr. James Thomson (University of Wisconsin, Madison) expect to provide a basic understanding of the hierarchy of cardiovascular precursor cellsand research the molecular events leading to the formation of blood-forming cells and heart forming cells as a prelude to therapeutic applications.

research focus:

Dr. Daniel Garry’s work focuses on the development of heart cells. This includes heart stem cells and heart progenitor cells. His research is directed towards discovering treatments for patients with common and deadly congenital heart disease and advanced heart failure.

Recent publications:

Singh S, Manda SM, Sikder D, Birrer MJ, Rothermel BA, Garry DJ, Mammen PP. Calcineurin activates cytoglobin transcription in hypoxic myocytes. J Biol Chem 2009; 284:10409-10421. http://www.jbc.org/content/284/16/10409.abstract Abstract Shi X, Bowlin KM, Garry, DJ. Fhl2 interacts with Foxk1 and corepresses Foxo4 activity in myogenic progenitors. Stem Cells 2009; 28:462-469. http://www3.interscience.wiley.com/journal/123208932/abstract|Abstract Ferdous A, Caprioli A, Iacovino M, Martin CM, Morris J, Richardson JA, Latif S, Hammer RE, Harvey RP, Olson EN, Kyba M, Garry DJ. Nkx2-5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo. Proc Natl Acad Sci USA 2009; 106:814-819. http://www.pnas.org/content/106/3/814.abstract|Abstract Sadek H, Latif S, Collins R, Garry MG, Garry DJ. Use of ferumoxides for stem-cell labeling. Regen Med 2008; 3:807-816. http://www.futuremedicine.com/doi/abs/10.2217/17460751.3.6.807|Abstract Martin CM, Ferdous A, Gallardo T, Humphries C, Sadek H, Caprioli A, Garcia JA, Szweda LI, Garry MG, Garry DJ. Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side-population cells. Circ Res 2008; 102:1075-1081. http://circres.ahajournals.org/cgi/content/abstract/102/9/1075 Abstract

Address:

Mayo Mail Code 508, 420 Delaware Street SE, Minneapolis, MN 55455

Phone:

(612) 626-2178

Fax:

(612) 626-4411

People:

blood-forming cells

cardiovascular precursor cells

heart cells

heart disease

heart failure