Carolyn Lutzko

Main Profile

Full Name and Degrees: 

Carolyn M. Lutzko, Ph.D

Member Role: 

Co-PI/Co-Investigator

Institutional affiliation: 

CCHMC

Research hub: 

Cell Characterization Core

Hub Site: 

None

Objective: 

Carolyn Lutzko, Ph.D
Cincinnati Children's Hospital Medical Center
Associate Professor, Experimental Hematology & Cancer Blood Disease
Director, Cell Processing Core/Cell Manipulations Lab
Director of Development
3333 Burnet Ave.
ML 7013
Cincinnati, Ohio 45229

Office # (513)803-2420
Fax # (513)636-1446
Carolyn.Lutzko@cchmc.org

research focus: 

Development of novel stem cell and gene based therapies for human disease. Development of therapies based on hematopoietic stem cells for genetic disease, mesenchymal stem cells for cardio-respiratory injury, and respiratory progenitors for CF and other lung disorders. Human embryonic stem cells, genes regulating self-renewal to improve the culture of self-renewing stem cells, and regulated differentiation towards the respiratory lineages. Generation of human iPSC.

Recent publications: 

Liebler J, Lutzko C, Banfalvi A, Senadheera D, Aghamohammadi N, Crandall ED, Borok Z. Retention of human bone marrow-derived cells in murine lungs following bleomycin injury. Am J Phys – Lung Cell & Mol Physiol 295:285-292, 2008 Chang D, Tsai S, Wang X, Xia P, Senadheera D, Lutzko C. Molecular characterization of the human nanog protein. Stem Cells 27: 812-21, 2009 Bui KC, Senadheera D, Wang X, Hendrickson B, Friedlich P, Lutzko C. Isolation of progenitors from the peripheral blood of patients with acute respiratory or cardiac failure who required ECMO support. American Journal of Respiratory and Critical Care Medicine 181: 226-237, 2010 Mishra S, Wang X, Smiley N, Bui KC, Senadheera D, Chang D, Lutzko C. In utero delivery of lentiviral supernatant to the amniotic fluid genetically modifies airway epithelial progenitors. American Journal of Respiratory Cellular and Molecular Biology: In Press, 2010

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