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Anil Jegga

Anil Jegga's picture

Main Profile

Full Name and Degrees: 
Anil G. Jegga
Member Role: 
Co-PI/Co-Investigator
Institutional affiliation: 
CCHMC
Hub Site: 
None
Objective: 

Anil G. Jegga
Cincinnati Children's Hospital Medical Center
Assistant Professor
Division of Biomedical Informatics
3333 Burnet Ave.
ML 7024
Cincinnati, Ohio 45229

Office # (513)636-0261
Fax # (513)636-2056
Anil.Jegga@cchmc.org

research focus: 

Elucidation of gene regulatory networks and the interaction between genotype and phenotype using a variety of bioinformatics approaches. Pioneered several computational approaches, widely used and cited. Developing and applying computational approaches for functional genomic data analysis, particularly for gene regulatory region prediction, polymorphism-impact analysis, identifying and prioritizing candidate genes. Novel systems biology to identify and prioritize novel disease candidate genes.

Recent publications: 
1.) Gu Y, Harley IT, Henderson LB, Aronow BJ, Vietor I, Huber LA, Harley JB, Kilpatrick JR, Langefeld CD, Williams AH, Jegga AG, Chen J, Wills-Karp M, Arshad SH, Ewart SL, Thio CL, Flick LM, Filippi MD, Grimes HL, Drumm ML, Cutting GR, Knowles MR, Karp CL. 2009 Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease. Nature 458(7241):1039-42. PMCID: PMC Journal-In Process 2.) Chen J, Aronow BJ, Jegga AG. 2009. Disease candidate gene identification and prioritization using protein interaction networks. BMC Bioinformatics 10:73. PMCID: PMC2657789 3.) Chen J, Bardes EE, Aronow BJ, Jegga AG 2009. ToppGene Suite for gene list enrichment analysis and candidate gene prioritization. Nucleic Acids Research doi: 10.1093/nar/gkp427. PMCID: PMC2703978 4.) Sardana D, Vasa S, Vepachedu N, Chen J, Gudivada RC, Aronow BJ, Jegga AG 2010. PhenoHM: human-mouse comparative phenome-genome server. Nucleic Acids Res. May 27. (Epub ahead of print). PMCID: IN process
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Anil G. Jegga

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