Progenitor Cells and their Niches

The goal of the Progenitor Cells and their Niches research hub is the interrogation of individual cells to identify progenitor cells and their niches.

Group Name: Lung Group
User Name FullName PCBC Related Research
mkrasnow Mark A. Krasnow, M.D., Ph.D.
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driordan Dan Riordan
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The discovery and characterization of human cell types and tissue features based on *in situ *analysis of their multi-dimensional molecular properties.
mayak Maya Kumar, Ph.D.
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Characterizing progenitor cells of the developing lung mesenchyme at the single cell level
jwang Jianbin Wang
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Developing single cell/single molecule genomic tools and using the tools for cell diversity and cell lineage studies
pharbury Pehr Harbury
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sytan Serena Yen Shan Tan
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Investigating the origins and development of lung macrophages in vivo, using lineage tracing and immunohistochemistry.
ckuo Christin Kuo
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Alterations in the number and localization  of pulmonary neuroendocrine (NE) cells occur in many pediatric and adult lung diseases. I am currently using genetic labeling techniques in mice to understand how NE cells form distinct clusters of innervated cells termed neuroepithelial bodies (NEBs) in mice.
tdesai Tushar Desai, M.D., M.P.H.
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Development and maintenance of the alveolar, or gas exchange region, of the lung as well as its role in the initiation and progression of diseases such as adenocarcinoma, pulmonary fibrosis, and emphysema.
Group Name: Blood Group
User Name FullName PCBC Related Research
iweissman Irving Weissman, M.D.
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rmajeti Ravi Majeti, M.D., Ph.D.
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bdai Bo Dai, Ph.D.
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Create a comprehensive methylome map of human hematopoietic stem and progenitor cells (HSPCs), and to identify novel hematopoietic progenitor cells (HPCs) via microarray at a single cell resolution.
lquinn Linda Quinn
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Rong Lu Rong Lu
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Single cell studies of hematopoietic stem cells. I use genetic barcodes to track mouse hematopoietic stem cells in vivo.
Debashis Sahoo Debashis Sahoo
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Developing new methods to analyze high-throughput biological datasets. Some of my tools that analyze gene expression datasets are StepMiner, BooleanNet and MiDReG. I have used Boolean implication and MiDReG to discover novel markers of the stem and progenitor cells in both normal and cancer tissues.
skarten Seth Karten
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Group Name: Heart Group
User Name FullName PCBC Related Research
dbravo Dawn Bravo, Ph.D.
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Identification and characterization of the progenitor cells of the upper airways of the nasal cavity and investigation of their relationship to the progenitor cells of the lower airways with potential therapeutic applications in airway diseases.

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