NIH Genomic Data Sharing (GDS) Policy

To promote sharing of human and non-human genomic data and to provide appropriate protections for research involving human data, the National Institutes of Health (NIH) issued the Genomic Data Sharing (GDS) Policy on August 27, 2014, in the NIH Guide Grants and Contracts (available at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-14-124.html). The GDS Policy is also available at http://gds.nih.gov/03policy2.html.

A microRNA-Hippo Pathway that Promotes Cardiomyocyte Proliferation and Cardiac Regeneration in Mice

A team led by Ed Morrisey, PhD, a professor of Medicine and Cell and Developmental Biology and the scientific director of the Institute for Regenerative Medicine in the Perelman School of Medicine at the University of Pennsylvania, has now shown that a subset of RNA molecules, called microRNAs, is important for cardiomyocyte cell proliferation during development and is sufficient to induce proliferation in cardiomyocytes in the adult heart.

NIH Funding Opportunity Announcements

NIH Big Data to Knowledge (BD2K) Enhancing Diversity in Biomedical Data Science (R25)

FOA #: RFA-MD-15-005

Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells

PCBC Investigator Helen Blau, professor of microbiology and immunology at Stanford University and director of the university's Baxter Laboratory for Stem Cell Biology, and colleagues have published an important discovery toward lengthening telomeres in The Federation of American Societies for Experimental Biology (FASEB) Journal (http://www.fasebj.org).

NHLBI Director's Fiscal Report to the NHLBI Community

The Director of the NHLBI, Dr. Gary Gibbons, has provided a report about the progress made during Fiscal Year 2014 and the forecast for funding opportunities in FY15.

Please see the attachment to read Dr. Gibbons message to the NHLBI scientific community.

Stanford Cardiovascular Institute Biobank Services

Stanford University's iPSC Biobank is an NHLBI-funded iPS resource.

Contact the SCVI for specific cardiac disease phenotypes and genetic mutations available. Access the SCVI Biobank, inquire about available iPSC lines and learn how patient's cells can be reprogrammed.

See flyer, below, for additional information.

NHLBI Announces Frequently Asked Questions (FAQs) for RFA-HL-15-005

NHLBI Announces Frequently Asked Questions (FAQs) for RFA-HL-15-005 “Revision Applications for Research Using Aged Animal Models to Study Chronic Disorders of Heart, Lung, Blood, and Sleep (R01)”, NOT-HL-14-237, National Heart, Blood, and Lung Institute.

The purpose of this Notice is to alert prospective applicants that NHLBI has posted a set of answers to Frequently Asked Questions (FAQs) regarding applications for RFA-HL-15-005.

Funding Opportunity Announcements: National Institutes of Health (NIH)

Vascular Dysfunction in the Pathogenesis of Severe Malaria (R01)

FOA #: RFA-HL-15-023

Funding Opportunity Purpose

The purpose of this FOA is to solicit multiple-Program Director/Principal Investigator (PD/PI) applications that propose collaborative studies to address the role of vascular activation and dysfunction in the pathogenesis of severe malaria. Multidisciplinary teams of investigators are needed to identify pathways and regulatory mechanisms by which vascular factors contribute to the complex etiology of severe malaria.

RFA: Library of Integrated Network-Based Cellular Signatures (LINCS): Perturbation-Induced Data and Signature Generation Centers (U54)

The Common Fund LINCS (Library of Integrated Network-based Cellular Signatures) program has released an RFA to support large-scale LINCS Perturbation-Induced Data and Signature Centers. These centers will be funded for up to 6 years to expand and improve the pilot LINCS program that has been running for 3 years: http://www.lincsproject.org/ and http://commonfund.nih.gov/LINCS/.

 

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