The Sartorius & Science Prize for Regenerative Medicine & Cell Therapy is an annual prize geared toward researchers focused for an essay on basic or translational research that advances regenerative medicine and cell therapy.
Two postdoctoral researcher positions are available in the laboratory of Dr. Rita Perlingeiro at the Lillehei Heart Institute, University of Minnesota, to study skeletal muscle differentiation from pluripotent stem cells (Cell Stem Cell, 10:610, 2012; Nat. Comm. 4:1549, 2013; Cell Reports, 19:2867, 2017). One project is focused on gene editing of patient-specific LGMD2I iPS cells, and the other on the development and optimization of cGMP iPS-derived myogenic progenitors for clinical trial readiness.
Drs. Alessandro Magli, James Thomson, Rita Perlingeiro, and colleagues identify CD54, integrin a9b1, and SDC2 as surface markers that enable the purification of myogenic progenitors endowed with long-term regenerative potential. [27Jun2017 Cell Reports]
Drs. Akhilesh Kumar, James Thomson, Igor Slukvin, and colleagues find that mesodermal pericytes and smooth muscle cells in human pluripotent stem cell cultures originate from a common endothelial and mesenchymal cell precursor, the mesenchymoangioblast. They show how different lineages of mural cells are specified from mesenchymoangioblasts and define stage- and lineage-specific markers for vasculogenic cells. [30May2017 Cell Reports]
The 2017 Cardiovascular Regenerative Medicine Symposium will take place September 27-28, 2017, at the National Institute of Health Campus in Bethesda, MD.
With the support of the NHLBI Progenitor Cell Biology Consortium (PCBC), Mark Krasnow, Tushar Desai, Pehr Harbury, and colleagues hosted a “PCBC Multiplexed in situ Hybridization Workshop” on March 22,2017, at Stanford University.
Drs. Katherine McCauley, Finn Hawkins, Darrell Kotton, and colleagues report that cyclical modulation of the canonical Wnt signaling pathway enables rapid directed differentiation of human iPSCs via an NKX2-1+ progenitor intermediate into functional proximal airway organoids. [30Mar2017 Cell Stem Cell]
