Reprogramming Cell Fate with a Genome-Scale Library of Artificial Transcription Factors

posted by sitemanager on Fri, 12/09/2016 - 10:19am
Hub Site: 
02-James Thomson
Author(s): 
Asuka Eguchia,b, Matthew J. Wleklinskib, Mackenzie C. Spurgatb, Evan A. Heiderscheitb, Anna S. Kropornickab,c, Catherine K. Vub, Devesh Bhimsariab,d, Scott A. Swansone, Ron Stewarte, Parameswaran Ramanathand, Timothy J. Kampf, Igor Slukving,h, James A. Thomsone,i,j, James R. Duttonk, and Aseem Z. Ansarib,j,1
Publication Type: 
Original Research Article
Name of Journal, Book, etc.: 
PNAS
Year: 
2016

Asuka Eguchi in Aseem Ansari’s laboratory has generated a genome-scale library of ATFs that display an engineered interaction domain (ID) to enable cooperative assembly and synergistic gene expression. They are glad to share this resource with the PCBC community. PNAS, December 2016

 

Click on the links below for article and press release:

http://www.pnas.org/content/early/2016/12/02/1611142114.full

http://news.wisc.edu/designer-switches-of-cell-fate-could-streamline-stem-cell-biology/

 

 

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