Publication: “Synthetic Transcription Elongation Factors License Transcription Across Repressive Chromatin”

Aseem Ansari, Graham Erwin, Matthew Grieshop, and colleagues designed sequence-specific synthetic transcription elongation factors (Syn-TEFs) that convert inhibitors of transcription into gene-specific stimulators.

[30Nov2017 Science]

Click on links below for press release and article:

https://news.wisc.edu/designer-molecule-points-to-treatment-for-diseases-caused-by-dna-repeats/

http://science.sciencemag.org/content/early/2017/11/29/science.aan6414?rss=1

 

 

Copyright ©2013 NHLBI Progenitor Cell Biology Consortium.

University of Maryland School of Medicine logo

National Heart Blood and Lung Institute logo