HS17 - Parker Hub Site
My research team's focus is on understanding cellular mechanotransduction in the heart. Specifically, we are interested in how extracellular matrix and cytoskeletal architecture potentiate and modulate the activation of mechanochemical and mechanoelectrical signaling pathways and genetic programs in cardiac cells and tissues. In order to study these mechanisms at different spatial scales, we use cellular and tissue engineering techniques that allow us to build custom-designed cardiac myocytes and ventricular tissue constructs as experimental preparations.
Protocols and Reagents that are associated with this hub site can be accessed by logging into Synapse and searching the database from the appropriate list of protocols or reagents. Click here for instructions to access Synapse.
| User Name | Full Name | Institutional Affilication | |
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idomian | Ibrahim Domian, M.D., Ph.D. | Harvard Stem Cell Institute |
| User Name | Full Name | Institutional Affilication | |
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lzangi | Lior Zangi | Harvard Univeristy |
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dspaeter | Daniela Spaeter | MGH - CVRC |
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sjinpark | Sung Jin Park | Harvard University |
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gwang | Gang Wang, Ph.D. | Harvard Stem Cell Institute |
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fpasqualini | Francesco S. Pasqualini, Ph.D. | Harvard Medical School |
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aatmanli | Ayhan Atmanli | Massachusetts General Hospital |
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kbuac | Kristina Buac | MGH |
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lscudder | Lisa L. Scudder, Ph.D. | Harvard University |
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dpasser | Derek Passer | Massachusetts General Hospital |
Pages
| Author(s) | Title | Link |
|---|---|---|
| Sheehy, Sean P; Grosberg, Anna; Parker, Kevin Kit | The contribution of cellular mechanotransduction to cardiomyocyte form and function | view |
| Sharma, Arun; Wu, Sean M | Of fish and men: clonal lineage analysis identifies divergence in myocardial development | view |
| Chien, Kenneth R; Yi, B Alexander; Xu, Huansheng; Mummery, Christine L | Cardiomyocyte reprogramming and the new age of cellular alchemy | view |
| Nawroth, Janna C; Lee, Hyungsuk; Feinberg, Adam W; Ripplinger, Crystal M; McCain, Megan L; Grosberg, Anna; Dabiri, John O; Parker, Kevin Kit | A tissue-engineered jellyfish with biomimetic propulsion | view |
| Wu, Sean M; Milan, David J | Reprogramming the beat: kicking it up a notch | view |
| Chen, Jenny X; Krane, Markus; Deutsch, Marcus-Andre; Wang, Li; Rav-Acha, Moshe; Gregoire, Serge; Engels, Marc C; Rajarajan, Kuppusamy; Karra, Ravi; Abel, E Dale; Wu, Joe C; Milan, David; Wu, Sean M | Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5 | view |
| Chen, Wen-Pin; Wu, Sean M | Small molecule regulators of postnatal Nkx2.5 cardiomyoblast proliferation and differentiation | view |
| Vallaster, Marcus; Vallaster, Caroline Dacwag; Wu, Sean M | Epigenetic mechanisms in cardiac development and disease | view |
| Balachandran, Kartik; Alford, Patrick W; Wylie- Sears, Jill; Goss, Josue A; Grosberg, Anna; Bischoff, Joyce; Aikawa, Elena; Levine, Robert A; Parker, Kevin Kit | Cyclic strain induces dual-mode endothelialmesenchymal transformation of the cardiac valve | view |
| Wu, Sean M; Hochedlinger, Konrad | Harnessing the potential of induced pluripotent stem cells for regenerative medicine | view |
Pages
Copyright ©2013 NHLBI Progenitor Cell Biology Consortium.
