HS08 - Daley Hub Site
George Daley's lab focuses on stem cell biology, with an emphasis on somatic cell reprogramming, hematopoietic differentiation from human and mouse pluripotent stem cells, and common mechanisms in reprogramming and cancer. His laboratory has pioneered the study of murine and human cell culture models of leukemia and genetic bone marrow disease and the role of the Lin28/let-7 pathway in human cancer and metabolic disease.
Protocols and Reagents that are associated with this hub site can be accessed by logging into Synapse and searching the database from the appropriate list of protocols or reagents. Click here for instructions to access Synapse.
members:
| User Name | Full Name | Institutional Affilication | |
|---|---|---|---|
 |
gdaley | George Q. Daley, M.D., Ph.D. | Children's Hospital Boston |
| User Name | Full Name | Institutional Affilication | |
|---|---|---|---|
 |
Muhammad Ashraf | Muhammad Ashraf, Ph.D | UC |
 |
kdcrawford | Keith Crawford, M.D., Ph.D. | Harvard Medical School, Brigham & Women's Hospital |
| User Name | Full Name | Institutional Affilication | |
|---|---|---|---|
|
|
yi-fen.lu | Yi-Fen Lu | Boston Children's Hospital |
|
|
emacari | Elizabeth Macari | HHMI/Children's Hospital |
|
|
peter.geon | Peter Geon Kim | Harvard Medical School |
|
|
sdoulatov | Sergei Doulatov, Ph.D. | Boston Children's Hospital |
|
|
jmandelb | Joseph Mandelbaum | Boston Children's Hospital |
|
|
gmaclean | Glenn MacLean, Ph.D. | Children's Hospital Boston |
| User Name | Full Name | Institutional Affilication | |
|---|---|---|---|
|
|
tschlaeger | Thorsten Schlaeger | Children's Hospital Boston |
Publication:
| Author(s) | Title | Link |
|---|---|---|
| Lengerke, Claudia; Wingert, Rebecca; Beeretz, Michael; Grauer, Matthias; Schmidt, Anne G; Konantz, Martina; Daley, George Q; Davidson, Alan J | Interactions between Cdx genes and retinoic acid modulate early cardiogenesis | view |
| Shyh-Chang, Ng; Daley, George Q | Lin28: primal regulator of growth and metabolism in stem cells | view |
| Cherry, Anne B C; Gagne, Katelyn E; McLoughlin, Erin M; Baccei, Anna; Gorman, Bryan; Hartung, Odelya; Miller, Justine D; Zhang, Jin; Zon, Rebecca L; Ince, Tan A; Neufeld, Ellis J; Lerou, Paul H; Fleming, Mark D; Daley, George Q; Agarwal, Suneet | Induced Pluripotent Stem Cells with a Pathological Mitochondrial DNA Deletion | view |
| Morris, Samantha A; Daley, George Q | A blueprint for engineering cell fate: current technologies to reprogram cell identity | view |
| Shyh-Chang, Ng; Locasale, Jason W; Lyssiotis, Costas A; Zheng, Yuxiang; Teo, Ren Yi; Ratanasirintrawoot, Sutheera; Zhang, Jin; Onder, Tamer; Unternaehrer, Juli J; Zhu, Hao; Asara, John M; Daley, George Q; Cantley, Lewis C | Influence of threonine metabolism on Sadenosylmethionine and histone methylation | view |
| Cherry, Anne B C; Daley, George Q | Reprogrammed cells for disease modeling and regenerative medicine | view |
| Kim, Peter Geon; Albacker, Colleen E; Lu, Yi-fen; Jang, Ilho; Lim, Yoowon; Heffner, Garrett C; Arora, Natasha; Bowman, Teresa V; Lin, Michelle I; Lensch, M William; De Los Angeles, Alejandro; Zon, Leonard I; Loewer, Sabine; Daley, George Q | Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelialto- hematopoietic transition | view |
| Zhang, Jin; Nuebel, Esther; Daley, George Q; Koehler, Carla M; Teitell, Michael A | Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal | view |
| McKinney-Freeman, Shannon; Cahan, Patrick; Li, Hu; Lacadie, Scott A; Huang, Hsuan-Ting; Curran, Matthew; Loewer, Sabine; Naveiras, Olaia; Kathrein, Katie L; Konantz, Martina; Langdon, Erin M; Lengerke, Claudia; Zon, Leonard I; Collins, James J; Daley, George Q | The transcriptional landscape of hematopoietic stem cell ontogeny | view |
| Maclean, Glenn A; Menne, Tobias F; Guo, Guoji; Sanchez, Danielle J; Park, In- Hyun; Daley, George Q; Orkin, Stuart H | Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells | view |
Pages
Copyright ©2013 NHLBI Progenitor Cell Biology Consortium.
