HS07 - Weissman Hub Site

Irving L. Weissman's research encompasses the phylogeny and developmental biology of the cells that make up the blood-forming and immune systems. His laboratory identified and isolated the blood-forming stem cell from mice, and has defined, by lineage analysis, the stages of development between the stem cells and mature progeny (granulocytes, macrophages, etc.). This required developing and cloning stromal cells of the hematolymphoid microenvironments—from the bone marrow for myeloid and B cells, and from the thymus for T cells. While the adhesion molecules and factors from these stromal cells proved important as molecules (and the genes that encode them) for myeloid and B cells, the analysis of T cell development required in vivo studies of thymic development.

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members: 
Principal Investigator
User Name Full Name Institutional Affilication
iweissman's picture
iweissman Irving Weissman, M.D. Stanford University
Co-PI/Co-Investigator
User Name Full Name Institutional Affilication
rmajeti's picture
rmajeti Ravi Majeti, M.D., Ph.D. Stanford University
mwernig's picture
mwernig Marius Wernig, M.D. Stanford University
Post-Doctoral Fellow/Trainee
User Name Full Name Institutional Affilication
Debashis Sahoo's picture
Debashis Sahoo Debashis Sahoo Stanford University
bdai's picture
bdai Bo Dai, Ph.D. Stanford University
gaporada's picture
gaporada Graca Almeida-Porada Wake Forest School of Medicine
chazchan's picture
chazchan Charles K. Chan Stanford University
jnamyoung's picture
jnamyoung Namyoung Jung Johns Hopkins School of Medicine
reinisch's picture
reinisch Andreas Reinisch Stanford University School of Medicine
Administrator
User Name Full Name Institutional Affilication
lquinn's picture
lquinn Linda Quinn Stanford

Pages

Publication: 
Author(s) Title Link
Seita, Jun; Sahoo, Debashis; Rossi, Derrick J; Bhattacharya, Deepta; Serwold, Thomas; Inlay, Matthew A; Ehrlich, Lauren I R; Fathman, John W; Dill, David L; Weissman, Irving L Gene Expression Commons: an open platform for absolute gene expression profiling view
Lu, Rong; Neff, Norma F; Quake, Stephen R; Weissman, Irving L Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding view
McGowan, Kelly A; Pang, Wendy W; Bhardwaj, Rashmi; Perez, Marcelina G; Pluvinage, John V; Glader, Bertil E; Malek, Reem; Mendrysa, Susan M; Weissman, Irving L; Park, Christopher Y; Barsh, Gregory S Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome view
Gibbs Jr, Kenneth D; Gilbert, Penney M; Sachs, Karen; Zhao, Feifei; Blau, Helen M; Weissman, Irving L; Nolan, Garry P; Majeti, Ravindra Single-cell phosphospecific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments view
Hsu, Li-Chung; Enzler, Thomas; Seita, Jun; Timmer, Anjuli M; Lee, Chih-Yuan; Lai, Ting-Yu; Yu, Guann-Yi; Lai, Liang- Chuan; Temkin, Vladislav; Sinzig, Ursula; Aung, Thiha; Nizet, Victor; Weissman, Irving L; Karin, Michael IL-1ýý-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKýý view
Kim, K; Doi, A; Wen, B; Ng, K; Zhao, R; Cahan, P; Kim, J; Aryee, M J; Ji, H; Ehrlich, L I R; Yabuuchi, A; Takeuchi, A; Cunniff, K C; Hongguang, H; McKinney- Freeman, S; Naveiras, O; Yoon, T J; Irizarry, R A; Jung, N; Seita, J; Hanna, J; Murakami, P; Jaenisch, R; Weissleder, R; Orkin, S H; Weissman, I L; Feinberg, A P; Daley, G Q Epigenetic memory in induced pluripotent stem cells view

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