HS04 - Wu Hub Site

The Wu lab studies the biological mechanisms of adult stem cells, embryonic stem cells, and induced pluripotent stem cells. We use a combination of next generation sequencing, tissue engineering, physiological testing, and molecular imaging technologies to better understand stem cell biology in vitro and in vivo. For adult stem cells, we are interested in monitoring stem cell survival, proliferation, and differentiation. For embryonic stem cells, we are currently studying their tumorigenicity, immunogenicity, and differentiation. For induced pluripotent stem cells, we are interested in cardiovascular disease modeling, drug screening, and cell therapy. We also develop novel vectors and therapeutic genes for cardiovascular gene therapy applications.

Protocols and Reagents that are associated with this hub site can be accessed by logging into Synapse and searching the database from the appropriate list of protocols or reagents.  Click here for instructions to access Synapse.

Principal Investigator
User Name Full Name Institutional Affilication
joewu's picture
joewu Joseph Wu, M.D., Ph.D. Stanford-Gladstone
User Name Full Name Institutional Affilication
mkay's picture
mkay Mark Kay, M.D., Ph.D. Stanford
swu's picture
swu Sean Wu, M.D., Ph.D. Stanford University School of Medicine
vsebastiano's picture
vsebastiano Vittorio Sebastiano Stanford University
jswartz's picture
jswartz James Swartz, D.Sc. Stanford University
Post-Doctoral Fellow/Trainee
User Name Full Name Institutional Affilication
adenisin's picture
adenisin Aleksandra Denisin Stanford University
shu's picture
shu Shijun Hu Stanford University
aebert's picture
aebert Antje Ebert Stanford University
pburridge's picture
pburridge Paul Burridge, Ph.D. Stanford University School of Medicine
pshukla2's picture
pshukla2 Praveen Shukla Stanford University School of Medicine


Author(s) Title Link
Deutsch, Marcus-Andre; Sturzu, Anthony; Wu, Sean M At a crossroad: cell therapy for cardiac repair view
Gregoire, Serge; Karra, Ravi; Passer, Derek; Deutsch, Marcus- Andre; Krane, Markus; Feistritzer, Rebecca; Sturzu, Anthony; Domian, Ibrahim; Saga, Yumiko; Wu, Sean M Essential and unexpected role of yin yang 1 to promote mesodermal cardiac differentiation view
Whelan, Russell S; Konstantinidis, Klitos; Xiao, Rui-Ping; Kitsis, Richard N Cardiomyocyte lifedeath decisions in response to chronic ýý-adrenergic signaling view
de Almeida, Patricia E; Ransohoff, Julia D; Nahid, Abu; Wu, Joseph C Immunogenicity of pluripotent stem cells and their derivatives view
Sharma, Arun; Wu, Sean M Of fish and men: clonal lineage analysis identifies divergence in myocardial development view
Nakamura, Kenta; Hirano, Kenichi; Wu, Sean M iPS cell modeling of cardiometabolic diseases view
Lan, Feng; Lee, Andrew S; Liang, Ping; Sanchez-Freire, Veronica; Nguyen, Patricia K; Wang, Li; Han, Leng; Yen, Michelle; Wang, Yongming; Sun, Ning; Abilez, Oscar J; Hu, Shijun; Ebert, Antje D; Navarrete, Enrique G; Simmons, Chelsey S; Wheeler, Matthew; Pruitt, Beth; Lewis, Richard; Yamaguchi, Yoshinori; Ashley, Euan A; Bers, Donald M; Robbins, Robert C; Longaker, Michael T; Wu, Joseph C Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patientspecific induced pluripotent stem cells view
Lam, Mai T; Longaker, Michael T Comparison of several attachment methods for human iPS, embryonic and adipose-derived stem cells for tissue engineering view
Quarto, Natalina; Li, Shuli; Renda, Andrea; Longaker, Michael T Exogenous activation of BMP-2 signaling overcomes TGFýýmediated inhibition of osteogenesis in Marfan embryonic stem cells and Marfan patient-specific induced pluripotent stem cells view
Wang, Yongming; Zhang, Wendy Y; Hu, Shijun; Lan, Feng; Lee, Andrew S; Huber, Bruno; Lisowski, Leszek; Liang, Ping; Huang, Mei; de Almeida, Patricia E; Won, Jong H; Sun, Ning; Robbins, Robert C; Kay, Mark A; Urnov, Fyodor D; Wu, Joseph C Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging view


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